Interactions of liposomes with restorative materials

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Liposomes are nanosized, vesicular structures that are well-recognized for their function as drug delivery systems. The in vitro adsorption and retention of liposomes onto four common types of dental restorative materials (conventional and silorane-based resin composites as well as conventional and resin-modified glass ionomer cements) have been investigated due to their potential use in the oral cavity. The results demonstrate that liposomes adsorb on and retain to different types of dental restorative materials. The surface charge of the liposomes seems to be the main determinant in the immediate interaction between liposomes and dental restoratives.

A part of this study was performed by PhD Sanko Nguyen during her stay as a visiting scientist at NIOM.

The article may be accessed and downloaded free of charge until December 17, 2015 using this link: http://www.sciencedirect.com/science/article/pii/S0927776515302551